• icon01November 27, 2014
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Worried you might eat too much during the holiday season? Following the festivities with one or two Cleanse Days is an effective way to get back on track by compensating for the extra calories eaten. Results from a recent study show just that.

In a recent randomized trial on 107 middle-aged women who were overweight or obese, researchers compared intermittent calorie restriction – similar to Cleanse Days – with continuous calorie restriction (dieting). It was one of the first human trials to ever compare the two weight-management strategies. At the end of the six months, the researchers found that both groups were comparable in total weight loss and improvements in several risk markers for Type 2 Diabetes, cardiovascular disease and several cancers. However, the intermittent calorie restriction group appeared to have greater improvements in insulin sensitivity and oxidative stress markers.

The study assigned the women to consume either a continuous calorie-restricted diet (25 percent below estimated requirements daily) or a intermittent calorie restriction diet that restricted calories by 75 percent for two days a week. The other five days followed the estimated requirements for weight maintenance.

The women in the calorie-restricted group followed a Mediterranean-type diet. The diet contained 30 percent calories from fat (most being monosaturated fat like olive oil, as found in IsaLean Shake), 45 percent calories from low-glycemic carbohydrates, and 25 percent calories from protein. The intermittent calorie-restrictions group followed the same diet, but only for two days consumed only 492 to 541 calories each day – that’s not quite as low in calories as the average Cleanse Day of about 150 calories daily, but it’s pretty close.

The increased insulin sensitivity from intermittent calorie restriction may be related to the significant decrease of insulin in the body during a one or two day reduced intake calories, which was followed by regular calorie intake. Insulin sensitivity is seen as good as the opposite, insulin resistance, is a major risk factor for the development of Type 2 Diabetes. There is an association with obesity and insulin resistance, with insulin resistant individuals usually having more body fat.

Magnetic resonance images of two women, one with obesity on the left and one with a normal weight on the right, clearly show how excess body fat (in yellow), especially visceral fat (around the middle), puts strain on internal organs such as the heart. Ref: Nat Geo 2004.

The authors wrote that intermittent calorie restriction “may be offered as an equivalent alternative to” dieting “for weight loss and reducing disease risk.”

For those on an Isagenix system, these findings support the importance of Cleanse Days. They may offer similar if not more benefits than regular dieting and weight loss. Unlike normal fasting or intermittent calorie restriction, drinking Cleanse for Life also supports nutritional, antioxidant protection, and detoxification to the body in form of its herbs, vitamins, and minerals.

Cleanse Day In 3 Easy Steps

  1. Drink 113 grams of Cleanse for life (liquid or powder) four times daily with or followed by purified water.
  2. Drink at least 8 glasses of purified water
  3. Take 2 Natural Accelerators and up to 6 Fibre Snacks per day to curbs cravings and boost fat burning.

And remember, if you have any questions at all, I am always here to talk or simply Click here to email with your questions and I will reply to you.


Margaret McNamara



Harvie MN, et al. “The effects of intermittent or continuous energy restriction on weight loss and metabolic disease risk markers: a randomized trial in young overweight women.” Int J Obes (Lond) 35.5 (2011): 714-27.


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